The Cannondale geometry is pretty much middle of the road, meaning if you don't have disproportionally extra long legs or torso, you should be able to dial in the fit with a reasonable sized frame. Assuming that's the case, a 52cm frame may be a tad small for you, but certainly could work.

Here is how I would go about it:
- Get a setback seatpost if it doesn't come with one. Preferable with a lot of setback to work with
- Set the saddle height and fore-aft position where when you sit on the saddle, you will have about 30 degree knee bend at the bottom of the stroke, and the knee slight behind or just above the pedal spindle (KOPS)
- Once you have the above set, now search for your hand placement on the bar where you feel the most comfortable. That should determine if your current stem is too long or short. And make adjustment accordingly.

I would do all this after some warm up.