The only issues (other than if the dropouts aren't long enough for all the options) might be the tire clearance for the 22/34 and the rear brake position might need fiddling which would be pretty annoying.

I've just run dingle/dixed setups with 2 teeth differences. e.g. 39/18 and 41/16 on the same bike works well for me - rear wheel stays in the same place, so no difference in tire clearance (this is used as a SSCX) or brake position. I'd be okay with another tooth difference though I think e.g. 42/16 as well. On a dixed obviously you probably won't care about a rear brake.