If I was buying a used bike for touring and it had brifters, I would still buy the bike assuming it was going to fit and work for me and what I needed it for (and not require a ton of repair or replace unless just buying for frame) and then replace the brifters with bar ends. I would then have a set of brifters I could sell or keep in the parts bin for another project.

I personally dislike brifters because of the brake lever being a part of the shifter in Shimano or in SRAM having the double tap which sounds great but confused the heck out of me when I rode it last (I wasn't sure where I was on the cassette sometimes) and Campy is cool for the repairability but I am not keen on the shift button and I don't want a Campy system unless it is 60s era on a Colnago (or really nice lugged Italian racing frame).

I might consider going for a Di2 type setup if the wallet ever gets fat enough with cash rather than receipts and I can get a good custom builder to build me a modern lugged stainless frame with custom made lugs and a ridiculous paint job.