Yep, do it all the time. I shift up one ring in front and two in back (smaller cogs). Pedal about a 50 cadence, just walk up the hill. This is particularly effective on our tandem, probably because of the greater momentum. We also do it on the flat, just shift to our 53 X 11 or 12 and stand. I like to do a standing rest every 10 minutes on a long climb, by the clock. We stand for maybe 30".