I use the Trail Glove 2 and Bare Access. I've used heavier shoes of theirs in the past, like the Chameleon Stretch, but I like the light running shoes best.
They definitely feel a lot different than cycling shoes, and I wouldn't expect everyone to like the feel, but I don't notice a dramatic drop in efficiency.
I prefer the Bare Access to the Trail Gloves because the sole is a little thicker and stiffer, but its still a very light shoe.
I've fitted both shoes with bungee laces that work just like Merrell's Stretch line, for added convenience.