I tried it for my knees and no results at all.BUT it stopped a very sharp pain in my wrist.I discontinued twice and the wrist pain came back in 2 days.Ive been on it about 9 months now.BTW I'm taking Glucosamine Chondroitin,2 pills daily is the recommended dose.I took the 2 pills for 2 weeks then backed it off to 1 pill daily.