I use 48/33 with a custom 12-32 cassette by using TA Specialite chainrings. For the cassette, I took out the 11t cog and put in the 15t cog. It's a great drivetrain with lots of smooth transitions throughout the cassette and no big jumps. 32/33 gets me very close to 1:1 as a hill grinder gear.
A lot of times I can ride on either the big or small chainring for long durations like it's a 1x11 speed, depending on the terrain. Using a 48t and 33t chainring was largely a product of using the 16t range of the derailleurs, then the 11t cog becomes very unnecessary. So I cleaned up the big space between the 14 and 16 in the cassette.
Maybe super powerful riders, and primarily on road, will find the 50t chainring useful, but for me it was a waste of gear range.