How windy is it where you ride? Are you competing? Deeper rims mean that it will take less wind to make riding no-hands safe and one hand off more iffy. Riding alone for long distances, that can get old. If you ride in the wet a lot, aluminum rims brake far better. Now, if you compete in little wind, the areo advantage of the deeper rim is real.

(I have a vivid recent memory of nearly crashing at the halfway point of a 50 mile ride. I finally had the wind at my back and sat up and took my hands off the bars for the first time. I spent the first hour and half in the drops or TT position on the hoods nearly the whole time. A gust caught the bike from the side and I nearly went down. Counter-steered hard and just grabbed the bars in time to steady them. That was close! This happened with quite shallow Open Pro rims. Had I been using deeper rims, it is highly unlikely I would have stayed up.)

Ben