It can be, as the inward limit of chainline is usually ether the chainring/chainstay clearance or the front derailer's reluctance to pull in both far enough and with enough force as the spring relaxes. Other times it might be chainring bolts that first threaten contact the chainstay.
Oh wait, I see a wink-smiley...

Flipped spindles are somewhat a kluged fix when it leaves the left pedal unnecessarily far out to the left, but a few millimeters isn't noticeable and can be somewhat balanced out using lateral cleat or toe-clip adjustments.

One more possible fix is to reverse the spindle and add a fixed-cup spacer, which can produce or approach a symmetrical bb.