Not personal experience, but I have been looking at the C17 because I have heard mostly good things and because I don't want a leather saddle. The price has been a hang up as I have a serviceable saddle (Specialized Body Geometry) that costs about 1/3 the price (well, it would have been more if I bought it new). But I've been thinking that there's room for improvement, comfort wise, and went to my LBS to ask if anyone had tried and had any opinions on the C17. He said, yes, they had opinions: Pretty much everyone at the shop had tried one and it was now their preferred saddle. They have a loaner saddle that I may try out first, but it is currently loaned out. The shop guy also said just about everyone who tried out the loaner saddle also ended up buying the Cambium.

I can't remember if it was at the shop or elsewhere that there seemed to be a preference for the cut out version. Not only did it relieve pressure in sensitive areas, but the cut out gave the saddle a little more flex, which seemed to improve comfort on longer rides.

None it first hand, but it all sounded good to me, and I may have to overcome my thriftiness and pick one up.