Originally Posted by
DrIsotope
The Schwalbe One tubeless is a tire that trades everything for grip and low rolling resistance. It's like an F1 tire for a bike. If your roads are immaculate, expect around 1,200 miles from a rear. If they're real-world roads with potholes, chipseal, and the usual detritus, expect 900-1,000. There is absolutely zero flat protection built into a One, it all comes from the liquid sealant. And everything will puncture. I had to top off sealant every 2 weeks, just from the amount expelled during punctures.
But man, were they ever fast and smooth.
I've had completely the opposite experience. My first rear tire lasted ~3000 mi with zero flats (no sealant). I retired it when a sharp rock caused a puncture because the tread was toilet paper thin. My current rear tire has probably 5000 mi on it (was previous a front). Since switching the to the One I've gotten significantly few flats than before (Michelin Pro3 and Hutchinson Fusion 3).
Tubeless tires have inherently better flat protection than an equivalent tubed tire. Since the tire is totally sealed, a pinhole leak remains a pinhole, while with a tube, the hole can expand as the tube stretches and can flop around the rim. Tubeless are much less likely to suddenly deflate, and will stay locked on the bead even with total deflation.