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Join Date: Aug 2010
Location: Madison, WI
Posts: 11,203
Bikes: 1961 Ideor, 1966 Perfekt 3 Speed AB Hub, 1994 Bridgestone MB-6, 2006 Airnimal Joey, 2009 Thorn Sherpa, 2013 Thorn Nomad MkII, 2015 VO Pass Hunter, 2017 Lynskey Backroad, 2017 Raleigh Gran Prix, 1980s Bianchi Mixte on a trainer. Others are now gone.
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300 pounds total weight on the wheels, I would use 36 spokes rear, if not more. If you have a choice, a frame with 135 mm dropout spacing.
Front, if you want to save some spokes, go ahead. Decades ago a lot of utility bike were sold with 40 spokes on the rear and 32 on front. You do not need to have the same on front as rear.