Every RD hanger is a little different, and it might be comparing apples to potato skins, but my
Nouvo Gran Sport derailleurs are shifting a 6-speed 14-30 cog set out back with a 52-40 up front, easy-peasy. Quite a bit more range than you're contemplating. Your option 4 Home Run sounds like a bloop single to me
With a such a tiny jump between the the chainrings, I can't imagine any of your options not working, provided you're willing to mess with the chain length.