Late to reply, we run 2 teeth captain advanced. We had ridden in phase, for a while, then took the time to use the monitors and computer to give meaning to how things felt. During a ride, we stopped and tested various settings after a baseline of in phase. For us, at the time, after several setting changes, we decided on the 2 teeth advanced. This gave the smoothest spin, easiest to spin 100 rpm constantly and lowest heart rates.
On the off-road tandem we ride in phase. Pedal strikes are a large concern and spinning off-road at 100 revs is a bit to bouncy for the suspension and tires.
The best answer, it just depends what you like and what works well for you.
I second that last answer. It is workable to try various phases so that is the best answer. Even if all posters like one phase setting, why not test it yourself to see what your team likes? Have fun trying stuff out