Carbonfiberboy, I like to run on the big chain ring and somewhere in the middle of the cassette, and it is easier on the cogs' and chain rings' wear. The one exception I've seen is a good friend of mine is a habitual big-big cross chainer on her mountain bike commuter and her largest cog and chain ring became knife edged ninja weapons. My older daughter is just as bad, but she mainly cross chains a RSX compact double with a 7S. There is just no breaking them of the habit.

Brad