Originally Posted by dvdslw

The JAMA study found that those men in the group who took testosterone replacement therapy had a 30% increase in risk of stroke and heart attack vs. men in the group who did not do TRT. Other side effects of testosterone therapy can include sleep apnea, acne, and gynecomastia – male breast enlargement.
While there is little evidence of any link between testosterone therapy and prostate cancer, some physicians believe the issue is still on the table – and urge patients getting TRT to check their PSA levels once or twice a year.
Another study, published in the New England Journal of American, examined the effect of testosterone gel in men 65 and older. It was discontinued when participants experienced cardiac, respiratory, and skin problems. Many did, however, experience an increase in muscle strength before the study was halted.
Here’s the worst thing about TRT: using a testosterone patch, pill, gel, or injection for even just a couple of weeks can shut down the natural testosterone-producing actions of your pituitary gland, hypothalamus, and gonads. Your body stops making testosterone, and your testicles decrease in size. And the longer you stay on testosterone replacement therapy, the more difficult it is for your body to resume natural testosterone production should you ever stop using TRT. Yikes!