Decades of riding on all manner of surfaces, at all ranges of tire pressures, all types of tires, various hazards, etc has lead to this solution. It really works (for me). This recipe has worked for decades on every tire brand I've ridden. I have not had a flat in a long time. Tires handle/maneuver very well.

Front tire - 700C X 25 mm clincher (Challenge), ~100 psi, butyl tube

Rear tire - 700C X 28 clincher (Challenge Parigi-Roubaix), ~120 psi, butyl tube

I weigh about 225 lb.

Lower pressures in the rear or a smaller rear tire generally resulted in punctures or occasional pinch flat from potholes.

Flat-free riding is paramount with me. Everything else comes next. So, I want excellent feel that is flat free. The Challenge tires are the best feel since I gave up on tubulars. If they punctured, I would move on.