FWIW. I am not a bike tourer (I only lurk here for the stories and sometimes the drama), but I have spent some time in Peru and hiked the Inca Trail. If you want to see Machu Picchu, that will be at least an entire day and will involve losing altitude as Cusco is at a higher elevation (which will screw up your acclimation time). Consider doing that at the end of the trip as at least one rest day. I had a pretty bad time with altitude sickness with two full days of acclimation, but it was my first time at that kind of elevation. +1 to bottled water- that is sold all over the place. I also wish I had known more Spanish at the time. Would have made a great trip even better. And I went in mid-May, during which we had sleet and 30 degree temps in the mountains.