You'd get rid of pinch flats, if that has been a problem for you. They would ride like tubulars but with the weight burden of the heavier clincher rims. Sealant would be very effective in these as their are in the Tufo Tubulars. I don't know (haven't checked) to see how the weight compares to a clincher plus tube.
Bottom line, I think this would be more reliable than a clincher tire/tube combination if run with sealant and you could get a better ride out of it too.
J.