I dream about doing something like this someday. As Ironwood already stated, "All it takes is good health, time and money."
I have the health (I think, anyway.) The time and money are the tricky parts. If you quit your job, you have the time but not the money. If you don't, you have the money but not the time.
I also notice most people who do things like this are single. I'm not, but if I left on a trek like this I would be when I got back.
So for now I'll just have to live vicariously through the stories from people like this.