The gatorskin haters usually point out how hard the casing on these things are, and how they do poorly in the rain and roll slowly.

I've only touched gatorskins, never used them, but they were the least supple tires I'd ever seen

For the same price Schwalbe Marathons are better for touring. Marathon Supremes are possibly the best tire on earth if you need semi-slick, fast, almost never-flat touring tires. But they'll cost you.