I decided to try to keep my drivetrain clean by squirting a bit (about a half-ounce) or mineral spirits between the cogs of the cassette daily, just before a ride. After the sidewall of a previous tire failed otherwise unaccountably, I leaned the bicycle towards the derailleur side to prevent any dripping onto the tire. My last tire (both Panaracer Pasela PTs, a model I've used before) failed after 14 months (short), cracking and bulging, the tread not all worn away. I can't imagine what else could have caused this. The front, the same model, is in better shape.

I ride the bicycle immediately after applying the MS and don't put the tire in the little bit that makes it to the pavement. (I keep the MS in the bed of my pickup, in the driveway)