Let's wrap this up now. The Drisdol 50,000 IU of D2 is a once weekly Rx given to BEGIN therapy for Vitamin D deficiency. The follow up after 12 weeks of 50,000IU of once weekly D2 is... 2,000IU daily dose of D3.
The D2 is considered a prodrug to the aforementioned D3.
Slamming your organ systems to clear high doses of anything, not just vitamin D is just not wise. Your body has a limited capacity to absorb any one vitamin daily... so the best therapy is daily exposure so your body can absorb it daily. Think sleep --> you can't sleep the entire weekend to catch up from not sleeping during the entire week.
I find the behavior of the people on this thread to be horrible. How can people be so snarky when they only know what they read on the internet. I think I know how we get the political figures we get in this country. Everyone is so busy shouting each other down that nobody listens.