Yup, the nephrologists I worked for back in the 1970s-'80s already knew about the risks of acetaminophen. There's a risk of liver and kidney damage from the cumulative effect of longterm use at levels considered "normal" or therapeutic. The only time I've taken the stuff was when it was combined with codeine #3 for pain after dental work.
Normally I use ibuprofen. Nothing is without risks but it works better than any OTC oral analgesic I've tried.