New to wheel building, trying to make sure I get the right hub.... Here are the hub sizes for the bike:
- Front and rear hub width: 100 mm and 135 hub spacing (As per what manufacture tells me. I assume this means 100mm front hub and 135mm rear hub)

I am thinking I want to go for a DT240s disc hub.

Is there a real compatibility difference between getting a 240S DB RW hub that is classified as a MTB hub vs Road Hub? It looks like the mountain bike version is the only one that uses the 6 bolt rotor mount (which is what I currently use), while the road bike version uses the center lock mount. Most noticeable difference I see is that the flanges on the center lock look to be the same width.

Road: https://www.dtswiss.com/Components/Hubs-Road/240s-db-RW
MTB: https://www.dtswiss.com/Components/Hubs-MTB/240s-RW-en

On my bike, I use the 6 bolt connection system. I CAN make the switch to center lock, but how much would that affect my current caliper mounts? I am using TRP Spyre calipers, so they have good adjustment.