Originally Posted by
Shimagnolo
And the great thing is you don't need to stop to clean out the squirrel guts when they run through them!

I found a video about the Cyclotron no-spoke bike.
What I think looked odd about it was that it apparently had a very full fender/sleeve that the wheel and tire went into (hopefully easy to fix a flat).
So... your squirrel could still get sucked up into the fender/sleeve, and make quite a mess out of it.
Of course, a hamster might be able to run on the wheel, giving an extra power boost