Out of the 4 bike trips I've did, 1700-8400 miles in length, all of them have been solo. I don't think a thing about it. Love it thoroughly. Couldn't truly imagine doing a bike trip with someone else and having to live by their standards versus just mine. I know of two people who have mentioned the idea of a two person trip this summer with me and with both, the one is a fast rider like me while the other one is overweight and slow, I still couldn't even imagine the idea of having to do things their way instead of my way. Our two concepts of doing things are quite radically different. I would be driving, err ridden nuts riding with them on any decent length trip. Too many stipulations...too much cramping my riding style.
You just have to learn to talk to yourself and then you won't mind not having someone to talk to. It is. You just learn to answer your own questions instead of expecting someone to give you an answer to a question. Learn to fight with yourself, its fun.