I used thorn resistant tubes once. I figured they would be good for my commute as I have seen cars purposly throw glass bottles in the cycle lane right in front of me.

My guess is they work. I only got 1 ride on them before I pulled each 300 gram per tube and chucked it in the trash. They'd work better if they were solid. Why even bother with air at that point? The ride was awful, slow, hard, wooden, and lethargic.

I switched to Gatorskin hardshells, & Mr. Tuffy liners. I now have 7 ,(no, 8?) bikes and they run from 23, 25, 32c tires, ultra-light & regular liners, regular & ultra-light inner-tubes. Any/all above combinations work better and ride better than those thorn resistant tubes.

I've had 1 flat in 5000 miles that wasn't due to my direct installation error. I've even used a roadside metal kitchen fork to dig glass, staples, and roofing nails out where the liner is plainly visible or the debris easily penetrated further than the thorn resistant rubber tube would have been thick, had it been installed. Yet, still got no flats even with ultra-lite tube & ultra-lite liner combination because the liner prevented tube penetration.

The Gator Hardshell and Mr. Tuffy is a hard combination to beat.

If ever you are in doubt, buy a liner 1 size wider than the tire you are using to help with some sidewall protection