I hate 'em especially for thinner tires for wider stuff they are still crap but at least easier to work with. I prefer to keep my tires properly inflated and do my best to avoid things that will flat me and good quality tires. If I am running through areas of higher flat likelihood I will probably run Gatorskins or GatorHardshells from Conti and of course the wider the better.

Mr. Tuffys are a horrible idea, a random piece of material with rough edges that will move around between your tube and tire and can cause flats?! Why go through the trouble. I would rather have the thorn resistant tubes in that case at least the tubes will stay in place pretty well.