Originally Posted by DropBarFan

Skyline is so pretty it helps make up for the effort. Have driven & biked the northern sections, not an expert on the southern half but AFAIK no must-see spot. Climbs aren't steep but very long, much tougher than occasional short hills. OTOH it's actually more common to see road-racing bikes than touring bikes so if you're pretty fit I'd guess the gearing would be OK. Tote sufficient water & snacks. Also, ironically, few convenient places for "natural breaks".