I regularly ride Ti. I did have the opportunity to buy a lightly-ridden Ghisallo last year. Perfect condition Campy Record 10-speed group and Proton wheels. So basically state of the art circa 2006 - everything I wanted. I really really wanted this bike. But I gave my head a shake, and passed.
The reason for not buying is that the frame is essentially underbuilt - for pure weight savings, and the head tube too short for the riding position I want on the bike. As much as I love Ti, this frame stretches the capabilities of the material too far - in my opinion.