Originally Posted by FBinNY

+1/2.

Adding/removing a tooth to the sprocket is only half the story. You're also bound by chain length increments of 1" which mean 1/2" in wheel position. So it's entirely possible that your desired gear combination will take the axle to the extreme position within the dropout.

Of course, using a 1/2 link, will allow 1/2" chain length increments, so only 1/4" of axle travel is needed.