Mostly, Yes.
I am mainly a weekend warrior for cycling, but I was getting the leg cramps all throughout the week. I just thought it was part of the Delayed Onset Muscle Soreness, that I also get.

But my doctor said no. He told me he is also on Simvastatin and was getting the cramps also, but he does not ride. He said after starting the every other day routine, his cramps ceased. Mine have too during the later part of the week. I still get some rarely on like Sunday evenings or Mondays. By the way the good doctor and I are on the 20mg version of Simvastatin. Also, my cholesterol has been under control for a couple years now.