I have an Osprey radial for cycling and an Osprey talon for hiking/light backpacking. I love the talon, but cannot ride with it. With that in mind, I love the radial for bike-commuting but feel its awkwardness off the bike. For an off-bike pack I value places for water bottles and pockets in the waist straps.

Osprey may get hyped, it makes one appreciate the power of getting into REI's inventory (MEC doesn't carry them), but I really like the packs for what I do with them. Also appreciate using the year that REI still gives customers to work out if/how best to use something, it was in week 51 that I realized I wanted my talon the next size up. Glad I caught that when I did!