I've gone touring with CX bikes before.

The only major problem I think OP might run into is fitting racks, but bikepacking gear is a thing and works pretty well if you plan on going light anyway. Some bikes like the CAADX have provisions for racks and fenders that more race-oriented bikes usually don't, though you can fit racks like the Axiom Streamliner.

Gearing isn't that big an issue IMHO. It's not that big a deal to get a deralier extender, larger cassette, or smaller chain ring(s) up front.