Originally Posted by
taz777
However, on a purely technical level, is it just 'plug and play'?
A clamp is a clamp. As long as adequate pressure can be developed, they are equivalent.
FWIW, I replaced the Q-R on my Trek mountain bike with a bolt years ago. I don't remember why, except I found a nice titanium seatpost clamp bolt and went for it!

(Saved about a gram!

)
Steve