Okay I guess I started this Sh** storm asking about using Compass tires on the Enve 4.5's. After much research (I think wheelbuilder has the warning also about tubeless only too) I agree with Seattle and Seth and will be going with the 4.5 and initially the Pro ones on my Domane build. I stick to paved roads but have a few hard packed sand roads in Jersey I'd like to explore and the 28's might handle those.
As a father of a scientist and engineer and as a decade long contractor on large projects who pays a lot of $$$ for stamped engineering drawings, I've grown weary of electrician, carpenters that tell me we don't have to do it that way and this will work etc. I feel it's prudent to always follow manufacturers/engineers specs if not for obvious safety but just common sense and liability issues .
Many things "might" work. What happens when they don't going 40 MPH down a windy road? Who do you call than if your still around?