That.

keep in mind that Sirrus models have either alu or carbon fork, with different width AFAIK. Take a tape measure and check the width of fork and chainstays. Check if there is pace on rear drops to move wheel back - larger tire might fit between chainstays, but might not clear the distanct to cross element between chainstays. Then see if you have enough clearance from chain in lowest gear (small chainring/largest casette element).

Some of Giant (Toughroad) and Specialized (AWOL) models are equipped with 40 or 50 mm tires, some other will be sold with 32 or 35mm and accomodate wider tires.

Also, search this forum. The subject of how wide tire into XXX is a recurring subject.

/ksywa