Originally Posted by
alexdi
It isn't and it's not. The procedure reduces to 'shift multiple sprockets.' The reason for it, again, is that the chain doesn't reach full tension for a given sprocket until after the shift is completed. In the initiating stage, there has to be enough B-screw to prevent rub, and the amount differs with how many sprockets you want to shift at once.
Interference doesn't require an 'oddly-stepped' cassette, though there are plenty of variants that make it more probable. SRAM in particular often eschews even jumps in favor of larger ones moving into the big sprockets. I can't speak to the nuances of their (or Campagnolo's) road derailleurs.
Larger jumps are going to make the surface of the cassette even more concave, making the jockey pulley position prior to the largest cog even less critical. I can't see how the number of sprockets shifted at a time has any bearing on whether the derailleur is positioned to make the last jump cleanly onto the largest sprocket or not.
Only on a humped, convex cassette (like a 12-23 10 speed) would setting the B adjustment just for the largest sprocket fail to make the best possible adjustment for all the sprockets.