As a former product manager of OFF! insect repellent, my recommendation is to use the least amount of Deet as possible and reapply as required. 15% deet will likely keep you pest free for 2+ hours. We all have different run times. But, make sure you apply it properly. Leave a spot open, the bugs will find it. Having said that, do not over spray. But rubbing it around, like you would a lotion and washing your hands is the best approach.

As some have said, Permetrhin is a good product, applied to clothes. . But, because it comes from plants does not mean it is not toxic. But, if you have bare skin, you will need a repellent.