Out on the web, there is a good video about pros riding with saddle tilted down which provides relief when riding in the drops. But...many pros really rotate their pelvis forward which takes pressure off the sit bones. One reason a guy like me prefers the Toupe is because you can tilt the saddle a bit nose down which provides perineal relief for low position riding and the rear of the saddle doesn't kick up too much placing too much pressure on the sit bones...because the Toupe is flatish. A precarious balance finding the sweet spot of loading.

Will also say, the better the rider the less the saddle is chair and more of perch. Better riders which are lighter and stronger with tighter rear end can ride just about anything without much discomfort...also they unweight the saddle more with greater pedal pressure. Opposite for recreational riders that aren't as fit who struggle more with finding the perfect saddle which carries more weight.