Yes. The ramps on your bars (the section of bar just aft of the hoods) should be at an angle which allows you to rest your wrists on them when your elbows are well bent in your standard go-fast position. Usually the brifters are next positioned so that the levers are vertical. It will take a bit of experimenting to get that just right. It doesn't matter in which direction your drops point. See:
Drop Bar Hand Positions: an Introduction
Handle bar tilt - How much is too much?