Go to a bike shop and have them take a look at it. My guess is the wheel is too big for your frame as it is probably 142x12mm thru axle or 135mm QR while your frame spacing is 130mm. A 1.5" tyre is 38mm which is too big for most road frames. And you will need to install disc brakes and rotors to use that wheel as it is not designed for rim brakes.

What bike are you installing it on?