Used Gatorskins for years riding locally with few flats. Used them on my first bike tour and had 7 flats in 13 days, including one horrible day outside Phoenix with 3 flats in about 20 miles.

For touring, I've switched to Schwalbe Marathon Plus tires and have had 1 flat in almost 5000 miles. I have a set on my road bike but I'm thinking of switching to Schwalbe Durano Plus tires. Anyone have any experience with this tire?