What are you trying to build, and why? Note that a htii road crankset will outright not work on a 73mm mtb bottom bracket, and your previous post was that you were planning on building up a 29er mtb frame.

Are you planning on using indexed shifters? They typically run poorly on significantly nonstandard chainring configurations. Chainrings with shift aids work much better when used as sets as intended.

If you can articulate why you need uncommon gearing, and what kind of bike you're trying to build we can probably help you