Originally Posted by Bryan C.

The cube reaction race seems to be the better of the 3 in terms of having the current standards. 1x12 drivetrain, thru axles, boost spacing (on the front at least, you may want to verify what the rear has before buying), and decent brakes.

The other cube has QR axles, and the cannondale says it has a custom rear axle QR spacing. Upgraded wheel sets may be difficult to find or very limited in selection for those. I ran into this problem recently, wound up buying a custom built set which worked out ok but wasn't cheap. Just something to consider.