I don't know what the spacing is on the rear IRO wheel, nor what it is on your road bike frame, but that's a possible problem area that could affect chainline.
Unless you know the threading of the roadie BB, it's impossible to say whether the IRO BB will work. If the rear spacing is different, you may well need a new BB anyway.
If the old frame took 27'' wheels, you might have a brake reach issue.
None of these problems should be deal-breakers, in my opinion. I would just start the swap and see what works and what doesn't and go from there.