A lot depends on your age. 25 years ago when I was in my early 40's I could ride every day. My daily commute was a 60 km round trip, I would do a couple of weekday evening rides and a couple of weekend rides of around 100 km. One year I had a stretch of 45 days of consecutive rides averaging about 550 km per week.
I can't do that anymore. I need rest days. However, long rides are still possible. Last spring, I did a 110 km ride near Mont Ventoux which included a 30 km climb, plus another short steep climb that exceeded 20% gradient. I was tired at the end, but I certainly didn't strain anything. A couple of years ago, I did a 95 km ride in the Pyrenees with about 3500 metres of climbing with a climb that is rated as HC in the Tour de France. Very tough, but again, I didn't strain anything, I was just tired at the end. If you felt strained after a 52 mile ride, the first thing I would look into would be bike fit, followed by looking into the gearing you have and use on your bike. After that, remember, longer rides are not approached the same as shorter more intense rides. On a long ride, start slowly and warm up thoroughly. Maintain a pace that you feel you can keep up forever, stay within your comfort zone at all times. On long rides with a group, I try to use energy so that I can feel strong at the end of the ride, I don't waste any energy I can avoid at the beginning.