It depends on what your riding is. if it is off-road most of the time and only little pavement, it could work. You may look into a 2nd wheelset, like a 29+ for on-road.
For most riders, this is where N+1 comes into play. i have a fatbike and a hybrid and i can't imagine only having either bike. A bike for everything will be severely compromised. Gearing, BB height, Geometry, tire tread etc. are all specific to type of riding.