For some years, I've been riding 4 seasons on my main road bike and Gatorskins on the bike I ride under adverse conditions (rain, dark, early spring, late fall, etc.). In my experience, the Gatorskins essentially never have a flat, even riding on the trashy surfaces of Minnesota just after the snow melt (tons of pot holes and lots of the sand/gravel/broken glass of the winter are concentrated on the shoulders. The 4 Seasons seldom get flats, but roll much better. On my weekend club rides, must people are running GP4000s or equivalents from other brands and they seem to get many more flats than my 4 Seasons.

I just did the stupid thing and ordered a pair of the new GP5000s for my weekend club ride bike. They are not going to make the difference so that I win the city limit sprints, and I'll probably get a bunch of flats. Then I'll go back to the 4 seasons, like a sensible person.